Multiple somatotopic representations of heat and mechanical pain 2 in the operculo - insular cortex : a high - resolution fMRI study 3

6 a: Department of Neurophysiology, Center for Biomedicine and Medical Technology 7 (CBTM), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany 8 b: Department of Neuroscience, Physiology and Pharmacology, University College 9 London, London, UK 10 c: Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK 11 d: Oxford Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB), 12 Clinical Neurology and Nuffield Department Anaesthetics, University of Oxford, 13 Oxford, UK 14 e: Department of Neuroradiology, Johannes Gutenberg University, Mainz, Germany 15 16 * These authors contributed equally 17 18 Running title: Multiple pain representations in the operculoinsular cortex 19 20 21 Address for correspondence 22 Dr. med. Ulf Baumgärtner 23 Department of Neurophysiology, Center for Biomedicine and Medical Technology (CBTM), 24 Medical Faculty Mannheim, Heidelberg University, Ludolf-Krehl-Str. 13-17, 25 68167 Mannheim, Germany 26 phone: +49-621-383-9934, Fax: +49-621-383-99321 27 e-mail: [email protected] 28 29 30 31